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If You Get Too Much Vitamin E appears to be safe when consumed in amounts up to 1,000 IU a day, although diarrhea and headaches have been reported in some people.

Doses of over 800 IU a day of vitamin E may interfere with the body's ability to clot blood, posing a risk to people taking blood thinners (anticoagulants).

Circulatory disorders, skin and joint problems, diabetes-related nerve complications, high cholesterol, endometriosis, immune-system function, and memory are also believed to benefit from vitamin E.

To date, however, research has been more intriguing than definitive.

Vitamin E is actually an umbrella term for a group of compounds called tocopherols and tocotrienols.

Until recently, most vitamin E products contained only tocopherols (alpha-, beta-, delta-, and gamma-tocopherols), with alpha-tocopherol recognized as the body's predominant and most potent form.

In addition, high doses of vitamin E may inhibit the absorption of vitamin A.

General Dosage Information Special tips: For most people, supplement dosages for vitamin E should be relatively low (400 IU or less), as there are apparent risks in taking very high doses.

On the other hand, a number of disappointing or ambiguous clinical trial results were published in the late 1990s and early 2000s.

A large study on Parkinson's disease, a neurologic condition, for example, indicated that taking vitamin E neither helped nor hurt its symptoms.

When summoned from the body's fatty tissue where it's stored, vitamin E--and it's antioxidant powers--go into action, protecting cells by deactivating or destroying the potentially damaging oxygen molecules called free radicals.